Coiled coil control of growth factor and inhibitor-dependent EGFR trafficking anddegradation
D. Mozumdar, S. H.-H. Chang, K. Quach, A. Doerner, A. Schepartz
The paper identifies a coiled coil switch in the EGFR juxtamembrane segment that controls trafficking and degradation, influencing signaling outcomes and TKI efficacy.
bioRxiv · Dec 10, 2020 · PreprintBiochemistry