BiochemistrybioRxivPreprint
Coiled coil control of growth factor and inhibitor-dependent EGFR trafficking anddegradation
D. Mozumdar, S. H.-H. Chang, K. Quach…·A. Schepartz
The paper identifies a coiled coil switch in the EGFR juxtamembrane segment that controls trafficking and degradation, influencing signaling outcomes and TKI efficacy.
DOI 10.1101/2020.12.10.419739