ImmunologybioRxivPreprint
BCAT1 inhibition affects CD8+ T cell activation, exhaustion, and tumoral immunity by altering iron homeostasis
F. Lodi, M. Certo, H. Elkafrawy…·A. E. Papathanassiu
This study shows BCAT1 inhibition alters iron homeostasis, affecting CD8+ T cell activation, exhaustion, and tumor immunity, with potential as a cancer therapy.