Author

J. Behmoaras

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Organism:mouse· 4 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

J.-H. Ko· 3 shared M. Pereira· 2 shared A. E. Papathanassiu· 1 shared A. L. M. Tan· 1 shared A. Zhang· 1 shared B. B. Manshian· 1 shared C. D. Rose· 1 shared C. Maksoudian· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersCell Biology

J.-H. Ko

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

WWP2 MEDIATES THE METABOLIC REPROGRAMMING OF RENAL MYOFIBROBLASTS TO PROMOTE KIDNEY FIBROSIS

H. Chen, R. You, J. Guo, W. Zhou, G. Chew, N. Devapragash, J. Z. Loh, L. Gesualdo, Y. Li, Y. Jiang, E. L. S. Tan, S. Chen, P. Pontrelli, F. Pesce, J. Behmoaras, , E. G. Petretto

This paper identifies WWP2 as a regulator of myofibroblast metabolic reprogramming in renal fibrosis, showing it suppresses PGC-1 to alter metabolic pathways and reduce fibrosis severity.

Journal of the American Society of Nephrology · Mar 19, 2024Peer-reviewedCell Biology

Fatty acid synthesis promotes inflammasome activation through NLRP3 palmitoylation.

S. Leishman, N. M. Aljadeed, L. Qian, S. Cockcroft, J. Behmoaras, P. K. Anand

This study shows that fatty acid synthesis promotes NLRP3 inflammasome activation through palmitoylation of NLRP3, with no effect on AIM2 inflammasome activation.

bioRxiv · Oct 30, 2023Immunology

BCAT1 inhibition affects CD8+ T cell activation, exhaustion, and tumoral immunity by altering iron homeostasis

F. Lodi, M. Certo, H. Elkafrawy, W. Li, H. A. Vu, K. Gilbo, L. Su, I. L. Pegg, T. Weiss, M. Bühler, M. Weller, C. Yeh, J. E. Corn, K.-S. E. Park, J.-H. Ko, , A. E. Papathanassiu

This study shows BCAT1 inhibition alters iron homeostasis, affecting CD8+ T cell activation, exhaustion, and tumor immunity, with potential as a cancer therapy.

bioRxiv · Feb 25, 2023 · PreprintImmunology

Multinucleation resets human macrophages for specialized functions at the expense of mononuclear phagocyte identity

K. Ahmadzadeh, M. Pereira, M. Vanoppen, E. Bernaerts, J.-H. Ko, T. Mitera, C. Maksoudian, B. B. Manshian, S. Soenen, C. D. Rose, P. Matthys, C. Wouters, J. Behmoaras

This study shows that multinucleation in human macrophages reduces mononuclear phagocyte identity and enables specialized functions in multinucleated giant cells.

bioRxiv · Aug 22, 2022Cell Biology

A trans-eQTL network regulates osteoclast multinucleation and bone mass

M. Pereira, J.-H. Ko, J. Logan, H. Protheroe, K.-B. Kim, A. L. M. Tan, K.-S. Park, M. Rotival, E. Petretto, J. H. D. Bassett, G. R. Williams, J. Behmoaras

The paper identifies a trans-eQTL network (MMnet) that regulates osteoclast multinucleation and bone mass in mice and humans.

bioRxiv · Feb 13, 2020Cell Biology