Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response
J. L. Mehl, A. Earle, J. Lammerding, M. Mhlanga, V. Vogel, N. Jain
This study shows that reducing Lamin-A/C levels enhances pro-inflammatory macrophage responses, and inhibiting its degradation or the IFN-β-STAT pathway can suppress inflammation.
bioRxiv · Feb 22, 2022Cell Biology