DNA-targeting and cell-penetrating antibody-drug conjugate
A. Shirali, V. Dubljevic, F. Cao, R. N. Nishimura, A. Ebens, J. A. Campbell, J. E. Hansen
The paper develops a DNA-targeting antibody-drug conjugate that selectively kills BRCA2-deficient tumors while sparing DNA repair-proficient ones.
bioRxiv · Apr 12, 2023 · PreprintImmunology