Author

R. N. Nishimura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

J. E. Hansen· 3 shared J. Gera· 3 shared A. Shirali· 2 shared A. Benavides-Serrato· 1 shared A. Ebens· 1 shared B. Holmes· 1 shared B. J. Cuffari· 1 shared C. Hino· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersImmunology

J. E. Hansen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 12, 2023

DNA-targeting and cell-penetrating antibody-drug conjugate

A. Shirali, V. Dubljevic, F. Cao…·J. E. Hansen

The paper develops a DNA-targeting antibody-drug conjugate that selectively kills BRCA2-deficient tumors while sparing DNA repair-proficient ones.

DOI 10.1101/2023.04.12.536500

humanproteomics

𝕏 PostBluesky

Cell BiologybioRxivPreprintFeb 22, 2023

Cellular protection from H2O2 toxicity by Fv-Hsp70 and mutants of Fv-Hsp70. Protection via catalase and gamma-glutamyl cysteine synthase.

C. Hino, G. Chan, G. Jordaan…·R. N. Nishimura

This study shows Fv-Hsp70 and its mutants protect SH-SY5Y cells from H2O2 toxicity through a protein-binding domain, and this protection involves catalase and gamma-glutamylcysteine synthase.

DOI 10.1101/2023.02.22.529417

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 11, 2023

cGAS-activating lupus autoantibody for cancer immunotherapy

X. Chen, X. Tang, B. J. Cuffari…·J. E. Hansen

This study shows a lupus anti-DNA autoantibody activates cGAS and improves survival in glioblastoma models by enhancing CD8+ T cell infiltration.

DOI 10.1101/2023.02.11.527649

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivMay 19, 2017

mTORC2/AKT/HSF1/HuR Constitute A Feed-Forward Loop Regulating Rictor Expression And Tumor Growth In Glioblastoma

B. Holmes, A. Benavides-Serrato, R. S. Freeman…·J. Gera

This study identifies a feed-forward loop involving mTORC2/AKT/HSF1/HuR that regulates Rictor expression and promotes glioblastoma growth.

DOI 10.1038/onc.2017.360

humanmetagenomics

𝕏 PostBluesky