Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
M. A. Lichtenstein, F. Cao, F. Lobnow, P. Dirvanskyte, A. Kulesza, E. Ziska, M. J. Taylor
The paper constructs a synthetic signalosome using Death Domains and shows that its function depends on polymer stability and avidity, demonstrating these properties are tunable and not restricted to specific motifs.
bioRxiv · May 8, 2024 · PreprintCell Biology
Z. Liang, A. Damianou, I. Vendrell, E. Jenkins, F. H. Lassen, S. J. Washer, G. Liu, G. Yi, H. Lou, F. Cao, X. Zheng, R. Fernandes, T. Dong, E. W. Tate, E. D. Daniel, B. M. Kessler
The paper identifies UCH-L1 as an NLRP3 interactor that modulates IL-1β production in human macrophages and microglia through proximity proteomics and functional assays.
bioRxiv · Oct 9, 2023 · PreprintBiochemistry
Y.-W. Luo, J.-P. Zhou, H. Ji, A. Zheng, X. Wang, Z. Dai, Z. Luo, F. Cao, X.-Y. Wang, Y. Bai, D. Chen, Y. Chen, Q. Wang, Y. Yang, X. Zhang, , K.-F. Tang
This study shows that SARS-CoV-2 N protein reduces Dicer, XPO5, SRSF3, and hnRNPA3, leading to pneumonia, and that inhibitors can reverse this effect.
bioRxiv · Oct 3, 2023 · PreprintMicrobiology
P. Kashyap, S. Bertelli, F. Cao, Y. Kostritskaia, F. Blank, N. Srikanth, R. Saleppico, D. Bierhuizen, X. Lu, W. Nickel, R. E. Campbell, A. Plested, T. Stauber, M. J. Taylor, H. Ewers
This paper develops an optogenetic method to release single molecules in live cells, enabling controlled delivery of functional proteins and reconstitution of cellular functions at the single molecule level.
bioRxiv · Sep 16, 2023Biophysics
A. Shirali, V. Dubljevic, F. Cao, R. N. Nishimura, A. Ebens, J. A. Campbell, J. E. Hansen
The paper develops a DNA-targeting antibody-drug conjugate that selectively kills BRCA2-deficient tumors while sparing DNA repair-proficient ones.
bioRxiv · Apr 12, 2023 · PreprintImmunology
F. Cao, R. Deliz-Aguirre, F. H. U. Gerpott, E. Ziska, M. J. Taylor
The paper shows that Myddosome clustering in IL-1R signaling regulates NF-kB activation by forming a signalosome that enhances TRAF6 and LUBAC recruitment.
bioRxiv · Jan 6, 2023Cell Biology
A. Guilbaud, F. Ghanegolmohammadi, Y. Wang, J. Leng, A. Kreymerman, J. Gamboa Varela, J. Garbern, H. Elwell, F. Cao, E. M. Ricci-Blair, C. Liang, S. Balamkundu, C. Vidoudez, M. S. DeMott, K. Bedi, , P. C. Dedon
This study identifies DNA damage patterns across tissues and sexes in rodents and humans, revealing age- and sex-dependent variations in DNA adducts and their potential as disease markers.
bioRxiv · Nov 28, 2022 · PreprintBiochemistry
E. Geerling, V. Murphy, E. T. Stone, A. G. Casals, M. A. Hassert, A. T. O'Dea, F. Cao, M. J. Donlin, B. E.-D. M. Elgendy, M. Elagawany, V. Pardali, E. Giannakopoulou, G. Zoidis, D. V. Schiavone, A. J. Berkowitz, , J. D. D. Brien
This study identifies 31 novel RVFV replication inhibitors with selective indexes and effective concentrations, primarily -Hydroxytropolones and N-Hydroxypyridinediones, validated in human cells and tested against related Bunyaviruses.
bioRxiv · Mar 10, 2022Microbiology
J. Li, S. Liu, P. Chen, J. Cai, S. Tang, W. Yang, F. Cao, P. Zheng, B. Sun
This study identifies R2R3-MYB transcription factors in C. sinensis and links some to the regulation of galloylated catechin biosynthesis.
bioRxiv · Jul 21, 2021Plant Biology
R. Deliz-Aguirre, F. Cao, F. H. U. Gerpott, N. Auevechanichkul, M. Chupanova, Y. Mun, E. Ziska, M. J. Taylor
This study investigates how MyD88 oligomerization is regulated by IRAK4 during Myddosome signaling, revealing that oligomer size acts as a threshold for downstream signaling.
bioRxiv · Sep 3, 2020Immunology