Involvement of an IgE/Mast cell/B cell amplification loop in abdominal aortic aneurysm progression
A. Loste, M. Clement, S. Delbosc, K. Guedj, J. Senemaud, A.-T. Gaston, M. Morvan, G. Even, G. Gautier, A. Eggel, M. Arock, E. Procopio, C. Deschildre, L. Louedec, J.-B. Michel, , M. Le Borgne
This study identifies an IgE/mast cell/B cell amplification loop that drives abdominal aortic aneurysm progression by promoting IL-4 production and subclinical fissure healing impairment.
bioRxiv · Sep 13, 2022Pathology