Author

J.-B. Michel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:development & morphogenesis· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Dumesnil· 2 shared C. Heron· 2 shared E. Brakenhielm· 2 shared P. Mulder· 2 shared A. Eggel· 1 shared A. Lebon· 1 shared A. Loste· 1 shared A. Nicoletti· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersPhysiology

A. Dumesnil

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Blocking Interleukin-1β transiently limits left ventricular dilation and reduces cardiac lymphangiogenesis during pressure-overload in mice

C. Heron, T. Lemarcis, O. Laguerre, M. Bundalo, C. Valentin, M. Valet, A. Dumesnil, J.-B. Michel, P. Mulder, A. Zernecke, V. Tardif San Martin, E. Brakenhielm

This study shows that blocking IL-1β early after pressure-overload reduces left ventricular dilation but not heart failure, while late blocking reduces lymphangiogenesis without worsening fibrosis.

bioRxiv · Apr 1, 2023 · PreprintPhysiology

Involvement of an IgE/Mast cell/B cell amplification loop in abdominal aortic aneurysm progression

A. Loste, M. Clement, S. Delbosc, K. Guedj, J. Senemaud, A.-T. Gaston, M. Morvan, G. Even, G. Gautier, A. Eggel, M. Arock, E. Procopio, C. Deschildre, L. Louedec, J.-B. Michel, , M. Le Borgne

This study identifies an IgE/mast cell/B cell amplification loop that drives abdominal aortic aneurysm progression by promoting IL-4 production and subclinical fissure healing impairment.

bioRxiv · Sep 13, 2022Pathology

Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure

C. Heron, A. Dumesnil, M. Houssari, S. Renet, A. Lebon, D. Godefroy, D. Schapman, O. Henri, G. Riou, L. Nicol, J.-P. Henry, M. Pieronne Deperrois, A. Ouvrard-Pascaud, R. Hagerling, H. Chiavelli, , E. Brakenhielm

This study investigates cardiac lymphangiogenesis in pressure-overload-induced heart failure, finding that it limits inflammation and fibrosis, delaying heart failure development.

bioRxiv · Apr 27, 2021Physiology