Continuum dynamics and statistical correction of compositional heterogeneity in multivalent IDP oligomers resolved by single-particle EM
B. Mostofian, R. McFarland, A. Estelle, J. Howe, E. Barbar, D. M. Zuckerman, S. L. Reichow
This paper develops a pipeline to analyze multivalent IDP oligomers using single-particle EM, correcting compositional heterogeneity and revealing new insights into their structure and function.
Journal of Molecular Biology · May 1, 2022Peer-reviewedBiophysics