Author

E. Barbar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:Bayesian inference· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. M. Zuckerman· 2 shared A. B. Estelle· 1 shared A. Estelle· 1 shared A. George· 1 shared B. Mostofian· 1 shared H. Stuwe· 1 shared J. Howe· 1 shared K. Hughes· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

D. M. Zuckerman

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Author profile →

3 papers

Recent·Most cited

Modifications to the SR-Rich Region of the SARS-CoV-2 Nucleocapsid Regulate Self-Association and Attenuate RNA Interactions

P. N. Reardon, H. Stuwe, S. Shah, Z. Yu, K. Hughes, E. Barbar

This study identifies how modifications to the SARS-CoV-2 N nucleocapsid protein's SR-rich linker region affect self-association and RNA interactions through structural and biochemical analyses.

bioRxiv · May 26, 2023 · PreprintBiophysics

Quantifying cooperative multisite binding in the hub protein LC8 through Bayesian inference

A. B. Estelle, A. George, E. Barbar, D. M. Zuckerman

This paper quantifies cooperative multisite binding in the protein LC8 using Bayesian inference, finding positive cooperativity in LC8-client peptide interactions but not in NudE-dynein intermediate chain interactions.

bioRxiv · Jun 29, 2022Biophysics

Continuum dynamics and statistical correction of compositional heterogeneity in multivalent IDP oligomers resolved by single-particle EM

B. Mostofian, R. McFarland, A. Estelle, J. Howe, E. Barbar, D. M. Zuckerman, S. L. Reichow

This paper develops a pipeline to analyze multivalent IDP oligomers using single-particle EM, correcting compositional heterogeneity and revealing new insights into their structure and function.

Journal of Molecular Biology · May 1, 2022Peer-reviewedBiophysics