A Two-Step Activation Mechanism Enables Mast Cells to Differentiate their Response between Extracellular and Invasive Enterobacterial Infection
C. von Beek, A. Fahlgren, P. Geiser, M. L. Di Martino, O. Lindahl, G. I. Prensa, E. Mendez-Enriquez, J. Eriksson, J. Hallgren, M. Fällman, G. Pejler, M. E. Sellin
This study shows mast cells use a two-step activation mechanism to distinguish between extracellular and invasive bacterial infections, leading to different cytokine responses.
bioRxiv · Aug 31, 2023Immunology