Adaptive strategies of the candidate probiotic E. coli Nissle in the mammalian gut
N. Crook, A. Ferreiro, A. Gasparrini, M. Pesesky, M. Gibson, B. Wang, X. Sun, Z. Condiotte, S. Dobrowolski, D. Peterson, G. Dantas
This study investigates how the probiotic E. coli Nissle adapts to the mammalian gut under various selective pressures and demonstrates its potential as an engineered therapeutic.
bioRxiv · Jul 9, 2018Evolutionary Biology