Direct Antigen Presentation is the Canonical Pathway of Cytomegalovirus CD8 T-cell Priming Regulated by Balanced Immune Evasion Mounting a Strong Antiviral Response
J. K. Buettner, S. Becker, A. Fink, M. M. Brinkmann, H. Rafaela, M. J. Reddehase, N. A. Lemmermann
This study investigates how CMV primes CD8 T cells, finding that balanced immune evasion supports optimal antiviral responses despite conflicting evidence on direct antigen presentation's role.
bioRxiv · Sep 1, 2023 · PreprintImmunology