MNRR1 activation by nitazoxanide abrogates lipopolysaccharide- induced preterm birth in mice
N. Purandare, N. Gomez-Lopez, M. Arenas-Hernandez, J. Galaz, R. Romero, Y. Xi, A. Fribley, L. I. Grossman, S. Aras
The paper shows that nitazoxanide prevents preterm birth in mice by activating MNRR1, which counteracts inflammation caused by intra-amniotic LPS.
bioRxiv · Jan 30, 2023 · PreprintImmunology