Over-expression of ADAR1 in mice does not initiate or accelerate cancer formation in vivo.
S. Mendez Ruiz, A. Chalk, A. Goradia, J. Heraud-Farlow, C. Walkley
This study shows that overexpressing ADAR1 in mice does not cause or speed up cancer formation, suggesting ADAR1 elevation is a passive, not active, factor in tumors.
bioRxiv · Jan 29, 2023 · PreprintCancer Biology