Transforming chemigenetic bimolecular fluorescence complementation systems into chemical dimerizers using chemistry
P. Kumar, A. Gutu, A. Waring, T. A. Brown, L. D. Lavis, A. G. Tebo
The paper develops novel fluorogens that activate FAST proteins and convert splitFAST systems into chemical dimerizers, reducing the need for protein engineering.
bioRxiv · Dec 30, 2023 · PreprintBiochemistry