SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback
C. H. Coelho, N. Bloom, S. I. Ramirez, U. M. Parikh, A. Heaps, S. F. Sieg, A. Greninger, J. Ritz, C. Moser, J. J. Eron, J. S. Currier, P. Klekotka, D. A. Wohl, E. S. Daar, J. Li, , Accelerating COVID-19 Therapeutic Interventions and Vaccines: 2/A5401 (ACTIV-2/A5401) Study Team
This study shows that SARS-CoV-2 mAb treatment shifts memory B cell epitope recognition, affecting their response to vaccination.
bioRxiv · Nov 21, 2023 · PreprintImmunology