Author

A. Isaac

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

A. A. Shibl· 3 shared S. A. Amin· 3 shared C. Fei· 2 shared M. A. Ochsenkuhn· 2 shared A. Cardenas· 1 shared A. J. Afzal· 1 shared A. R. Mohamed· 1 shared C. R. Voolstra· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersEcology

A. A. Shibl

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular mechanisms of microbiome modulation by the eukaryotic secondary metabolite azelaic acid

A. A. Shibl, M. A. Ochsenkuhn, A. R. Mohamed, A. Isaac, L. S. Y. Coe, Y. Yun, G. Skrzypek, J.-B. Raina, J. R. Seymour, A. J. Afzal, S. A. Amin

This study investigates how azelaic acid affects two microalgal-associated bacteria, identifying uptake mechanisms and toxicity pathways, and shows its role in shaping microbial communities in marine environments.

bioRxiv · Apr 8, 2022Ecology

Diatom Modulation of Microbial Consortia Through Use of Two Unique Secondary Metabolites

A. A. Shibl, A. Isaac, M. A. Ochsenkühn, A. Cardenas, C. Fei, G. Behringer, M. Arnoux, N. Drou, M. P. Santos, K. C. Gunsalus, C. R. Voolstra, S. A. Amin

This study shows diatoms use two unique secondary metabolites to promote beneficial bacteria and inhibit harmful ones in their microbial communities.

Proceedings of the National Academy of Sciences · Oct 16, 2020Peer-reviewedMicrobiology

Quorum Sensing Regulates 'swim-or-stick' Lifestyle in the Phycosphere

C. Fei, M. A. Ochsenkuhn, A. A. Shibl, A. Isaac, C. Wang, S. A. Amin

This study shows that quorum sensing regulates bacterial attachment to diatom surfaces, with symbionts producing QS signals that promote colonization while an opportunistic bacterium lacks these signals.

bioRxiv · Jul 26, 2020Ecology