C. Fei

Cell-scale gene-expression measurements in Vibrio cholerae biofilms reveal spatiotemporal patterns underlying development

This study uses smFISH to analyze gene expression in V. cholerae biofilms, revealing spatiotemporal patterns and the role of quorum sensing and c-di-GMP signaling in matrix gene expression.

Capillary interactions drive the self-organization of bacterial colonies

This study shows capillary forces organize bacterial colonies into dense, nematic groups and influence their collective dynamics.

Natural Silencing of Quorum-Sensing Activity Protects Vibrio parahaemolyticus from Lysis by an Autoinducer-Detecting Phage

This study shows that a QS-deficient strain of V. parahaemolyticus is more susceptible to phage lysis, suggesting that QS suppression protects the host from viral attack.

Bacterial LomR Induces the Vibriophage VP882 VqmA-Directed Quorum-Sensing Lysogeny-Lysis Transition

This paper identifies LomR, OmpX, and OmpT as bacterial proteins that induce phage lysis by triggering quorum-sensing in vibriophages.

LuxT is a Global Regulator of Low-Cell Density Behaviors Including Type III Secretion, Siderophore Production, and Aerolysin Production in Vibrio harveyi

This paper identifies LuxT as a global regulator in Vibrio harveyi that controls over 400 genes involved in low-cell density behaviors, including type III secretion, siderophore production, and aerolysin toxin biosynthesis, through SwrZ-dependent and -independent mechanisms.

Quantitative input-output dynamics of a c-di-GMP signal-transduction cascade in Vibrio cholerae

The paper quantifies how c-di-GMP signaling via NspS-MbaA in Vibrio cholerae translates ligand binding into specific biofilm gene expression changes.

Diffusion barriers and adaptive carbon uptake strategies enhance the modeled performance of the algal CO2-concentrating mechanism

The paper develops a chloroplast-scale reaction-diffusion model to analyze the algal CO2-concentrating mechanism (CCM), showing that diffusion barriers and adaptive carbon uptake strategies enhance its performance and efficiency.

LuxT controls specific quorum-sensing-regulated behaviors in Vibrionaceae spp. via repression of qrr1, encoding a small regulatory RNA

This paper identifies LuxT as a repressor of qrr1 in Vibrionaceae, showing it controls specific quorum-sensing behaviors by regulating unique downstream gene expression patterns.

Diatom Modulation of Microbial Consortia Through Use of Two Unique Secondary Metabolites

This study shows diatoms use two unique secondary metabolites to promote beneficial bacteria and inhibit harmful ones in their microbial communities.

Identification of signaling pathways, matrix-digestion enzymes, and motility components controlling Vibrio cholerae biofilm dispersal

This study identifies signaling pathways, matrix-digestion enzymes, and motility factors controlling Vibrio cholerae biofilm dispersal through a high-content imaging screen.

Quorum Sensing Regulates 'swim-or-stick' Lifestyle in the Phycosphere

This study shows that quorum sensing regulates bacterial attachment to diatom surfaces, with symbionts producing QS signals that promote colonization while an opportunistic bacterium lacks these signals.

Competitive binding of independent extension and retraction motors explains the quantitative dynamics of type IV pili

The paper quantifies type IV pili dynamics in Pseudomonas aeruginosa and shows that extension and retraction are governed by competitive motor binding, with retraction motor unbinding limiting production.