NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
C. Marques, T. Unterkircher, P. Kroon, A. Izzo, Y. Dramaretska, E. Kling, B. Oldrini, O. Schnell, S. Nelander, E. F. Wagner, L. Bakiri, G. Gargiulo, M. S. Carro, M. Squatrito
The paper identifies FOSL1 as a key regulator of mesenchymal glioblastoma subtype through NF1 modulation, showing its role in plasticity and aggressiveness.
bioRxiv · Nov 6, 2020Cancer Biology