G. Andrieux

This paper shows that epitope-engineered human hematopoietic stem cells are protected from CD123-targeted immunotherapy while maintaining functionality, offering a strategy for tumor-selective therapy.

The paper identifies LUBAC-mediated M1 ubiquitination as a species-specific checkpoint regulating necroptosis by controlling MLKL membrane accumulation in human cells and organoids.

This study shows that breast cancer stem cells escape γδ T cell immunosurveillance by losing key ligands and antigens, and that this escape can be reversed with Zoledronate or IFN- treatment.

This study identifies USP22 as a regulator of STING and type III IFN signaling, showing its role in SARS-CoV-2 infection and antiviral defense in human intestinal epithelial cells.

The paper uses spatial transcriptomics to identify molecular features of 5ALA+ infiltrative tumor cells in glioblastoma linked to recurrence and poor survival.

This study identifies spatially confined sub-tumor microenvironments in PDAC that drive distinct tumor progression outcomes.

This study shows CD20 maintains the resting state of human B cells by organizing surface receptors, and its disruption leads to B cell activation and plasma cell differentiation.

This study identifies ZBTB18 as a regulator of SREBP gene expression in glioblastoma by modulating CTBP and LSD1 activity, leading to epigenetic repression of fatty acid synthesis.