Author

A. J. Faure

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

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Research Focus:protein folding & dynamics· 3 Approach:deep learning· 2 Organism:human· 2 Assay:protein sequence· 2 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Lehner· 3 shared J. M. Schmiedel· 2 shared A. Marti-Aranda· 1 shared C. Hidalgo· 1 shared C. Hidalgo-Carcedo· 1 shared C. Weng· 1 shared G. Diss· 1 shared J. Domingo· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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3 shared papersBiophysics

B. Lehner

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Author profile →

3 papers

Recent·Most cited

The genetic architecture of protein stability

A. J. Faure, A. Marti-Aranda, C. Hidalgo, J. M. Schmiedel, B. Lehner

This study shows that the genetic architecture of some proteins is simple, allowing accurate prediction using interpretable biophysical models despite the complexity of deep neural networks.

bioRxiv · Oct 27, 2023Biophysics

The energetic and allosteric landscape for KRAS inhibition

C. Weng, A. J. Faure, B. Lehner

This paper maps inhibitory allosteric sites in KRAS by analyzing mutations and their effects on protein folding and binding, revealing potential therapeutic targets.

bioRxiv · Dec 6, 2022Biophysics

Global mapping of the energetic and allosteric landscapes of protein binding domains

A. J. Faure, J. Domingo, J. M. Schmiedel, C. Hidalgo-Carcedo, G. Diss, B. Lehner

The paper develops a method using deep mutational scanning to map allosteric landscapes of protein domains, revealing widespread allosteric mutations and their effects on binding affinity.

bioRxiv · Sep 14, 2021 · PreprintBiophysics