Author

A. J. Higgins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Russell Lewis· 1 shared D. Hammerschmid· 1 shared E. Reading· 1 shared F. Sobott· 1 shared H. I. Zgurskaya· 1 shared J. C. Gumbart· 1 shared J. M. Parks· 1 shared K. M. Kuo· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

B. Russell Lewis

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1 paper

Recent·Most cited

Conformational restriction shapes inhibition of a multidrug efflux adaptor protein

B. Russell Lewis, M. R. Uddin, M. Moniruzzaman, K. M. Kuo, A. J. Higgins, L. M. N. Shah, F. Sobott, J. M. Parks, D. Hammerschmid, J. C. Gumbart, H. I. Zgurskaya, E. Reading

The paper investigates how an inhibitor restricts the conformational dynamics of AcrA, a multidrug efflux adaptor protein, to block drug signal transmission in E. coli.

bioRxiv · Dec 9, 2022Biochemistry