Author

A. J. Morrison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Microbiology· 1 Pharmacology & Toxicology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Approach:statistical model· 3 Assay:protein structure· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. J. Harms· 4 shared B. H. T. Bridges· 1 shared B. Outlaw· 1 shared C. E. Wong· 1 shared D. E. Promislow· 1 shared D. R. Wonderlick· 1 shared E. L. Dolan· 1 shared I. Koscik· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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4 shared papersBiophysics

M. J. Harms

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Author profile →

6 papers

Recent·Most cited

Development and Validation of the Mentoring in Undergraduate Research Survey

L. B. Limeri, N. T. Carter, R. A. Hess, T. T. Tuma, I. Koscik, A. J. Morrison, B. Outlaw, K. S. Royston, B. H. T. Bridges, E. L. Dolan

The paper develops and validates the Mentoring in Undergraduate Research Survey (MURS) to measure mentoring experiences, identifying seven subtypes and two higher-order factors with associated outcomes.

bioRxiv · Aug 19, 2023 · PreprintScientific Communication & Education

An experimental demonstration of ensemble epistasis in the lac repressor

A. J. Morrison, M. J. Harms

The paper experimentally demonstrates ensemble epistasis in the lac repressor, showing that mutations alter conformational ensembles, leading to significant epistatic effects in DNA binding and gene expression.

bioRxiv · Oct 14, 2022 · PreprintBiophysics

Higher-order interactions shape microbial interactions as microbial community complexity increases

M. A. Morin, A. J. Morrison, M. J. Harms, R. J. Dutton

The paper investigates how microbial interactions change with community complexity, finding that higher-order interactions emerge and most conserved interactions are additive.

bioRxiv · May 19, 2022Microbiology

Pharmacokinetics of long-term low-dose oral rapamycin in four healthy middle-aged companion dogs

J. B. Evans, A. J. Morrison, M. A. Javors, M. Lopez-Cruzan, D. E. Promislow, M. Kaeberlein, K. E. Creevy

This study measures rapamycin blood concentrations and pharmacokinetics in dogs on long-term low-dose oral administration.

bioRxiv · Jan 20, 2021 · PreprintPharmacology & Toxicology

Ensemble epistasis: thermodynamic origins of non-additivity between mutations

A. J. Morrison, D. R. Wonderlick, M. J. Harms

The paper shows that ensemble epistasis, arising from thermodynamic ensembles in macromolecules, is a common source of non-additivity between mutations.

bioRxiv · Oct 14, 2020Biophysics

Conservation of specificity in two low-specificity proteins

L. C. Wheeler, J. A. Anderson, A. J. Morrison, C. E. Wong, M. J. Harms

This study shows that low-specificity S100 proteins maintain conserved peptide binding specificity across species, indicating evolutionary constraints and subfunctionalization of paralogs.

bioRxiv · Oct 25, 2017Biochemistry