Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum
M. M. Schneider, T. Scheidt, A. J. Priddey, C. K. Xu, M. Hu, S. R. A. Devenish, G. Meisl, C. M. Dobson, V. Kosmoliaptsis, T. P. J. Knowles
This paper develops a microfluidic assay to directly measure antibody affinity and concentration in solution, applied to characterise alloantibody-HLA interactions in transplant patient sera.
bioRxiv · Sep 14, 2020 · PreprintBiophysics