Cytokine priming of naive CD8+ T lymphocytes modulates chromatin accessibility that partially overlaps with changes induced by antigen simulation
A. J. Quenum, M. Cloutier, M. A. Santharam, M. Mayhue, S. Ramanathan, S. Ilangumaran
This study shows cytokine priming of naive CD8+ T cells changes chromatin accessibility, with some overlaps seen with antigen stimulation, suggesting a poised state for enhanced TCR responsiveness.
bioRxiv · Aug 11, 2020 · PreprintImmunology