S. Ramanathan

Endothelial cannabinoid CB1 receptor deficiency reduces arterial inflammation and lipid uptake in response to atheroprone shear stress

This paper shows that blocking endothelial CB1 receptors reduces arterial inflammation and lipid uptake under atheroprone shear stress, suggesting potential therapeutic benefits for atherosclerosis.

Testing a Method for Quantifying Microplastic Content in Mytilus californianus

The paper tests a method to isolate and quantify microplastics in Mytilus californianus using digestion, sonication, and fluorescent microscopy.

SARS-CoV-2 spike antigen-specific B cell and antibody responses in pre-vaccination period COVID-19 convalescent males and females with or without post-covid condition

This study examines B cell and antibody responses to SARS-CoV-2 antigens in individuals with and without post-COVID condition (PCC), finding sex-related differences in antibody responses to the spike protein.

Intra- and inter-species interactions drive early phases of invasion in mice gut microbiota

The paper tracks E. coli invasion in mice gut microbiota using chromosomal barcodes and dynamic covariance mapping, identifying three phases of invasion driven by ecological and evolutionary dynamics.

SOCS3-mediated activation of p53-p21-NRF2 axis and cellular adaptation to oxidative stress in SOCS1-deficient hepatocellular carcinoma

The paper shows that SOCS1 deficiency leads to increased SOCS3 expression, which activates the p53-p21-NRF2 axis, reducing oxidative stress and HCC progression.

Inhibition of HIV-1 immune modulation by small molecules targeting viral Nef-host CD80 interface

The paper identifies small molecules that inhibit HIV-1 Nef's down-regulation of CD80/86, restoring T-cell activation by targeting the Nef-CD80 interface.

Combinations of Indole based alkaloids from Mitragyna speciosa (Kratom) and cisplatin inhibit cell proliferation and migration of Nasopharyngeal carcinoma cell lines

This study investigates the combination of indole-based alkaloids from kratom with cisplatin to inhibit nasopharyngeal carcinoma cell proliferation and migration.

Cytokine priming of naive CD8+ T lymphocytes modulates chromatin accessibility that partially overlaps with changes induced by antigen simulation

This study shows cytokine priming of naive CD8+ T cells changes chromatin accessibility, with some overlaps seen with antigen stimulation, suggesting a poised state for enhanced TCR responsiveness.

Prognostic significance of SOCS1 and SOCS3 tumor suppressors in hepatocellular carcinoma and its correlation to key oncogenic signaling pathways

The paper evaluates SOCS1 and SOCS3 expression in hepatocellular carcinoma and their correlation with oncogenic pathways, finding some genes predict prognosis when combined with SOCS1/SOC3 levels.