Author

A. Jager

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Guskov· 1 shared A. Hernandez-Segura· 1 shared B. Poolman· 1 shared B. Wang· 1 shared D. A. Griffith· 1 shared E. M. Jongbloed· 1 shared E. Ploetz· 1 shared G. Gouridis· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Guskov

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2 papers

Recent·Most cited

Structural and biophysical characterization of the tandem substrate-binding domains of the ABC importer GlnPQ

E. Ploetz, G. Schuurman-Wolters, N. Zijlstra, A. Jager, D. A. Griffith, A. Guskov, G. Gouridis, B. Poolman, T. Cordes

This paper characterizes the structural and biophysical properties of the tandem substrate-binding domains of the ABC importer GlnPQ using crystal structures, calorimetry, and smFRET.

bioRxiv · Dec 19, 2020Biophysics

Pharmacological CDK4/6 inhibition unravels a p53-induced secretory phenotype in senescent cells

B. Wang, S. Brandenburg, A. Hernandez-Segura, T. van Vliet, E. M. Jongbloed, S. M. Wilting, N. Ohtani, A. Jager, M. Demaria

This study shows that CDK4/6 inhibitors induce a non-inflammatory senescent state in non-malignant cells, which lacks the pro-tumorigenic SASP but retains paracrine senescence induction.

bioRxiv · Jun 5, 2020 · PreprintCell Biology