Antisense Oligonucleotide Targeting Hepatic Serum Amyloid A Limits the Progression of Angiotensin II-Induced Abdominal Aortic Aneurysm Formation
P. Shridas, A. Ji, A. C. Trumbauer, V. P. Noffsinger, L. W. Meredith, F. C. de Beer, A. E. Mullick, N. R. Webb, D. G. Karounos, L. R. Tannock
This study shows that reducing SAA with antisense oligonucleotides limits AAA progression in obese mice treated with AngII.
bioRxiv · Aug 22, 2023Pathology