Apoptotic signaling clears engineered Salmonella in an organ-specific manner
T. J. Abele, Z. P. Billman, L. Li, C. K. Harvest, A. K. Bryan, G. R. Magalski, J. P. Lopez, H. N. Larson, X.-M. Yin, E. A. Miao
This study shows that apoptosis and pyroptosis clear engineered Salmonella from different organs in mice, with pyroptosis being more effective in myeloid niches and apoptosis in the intestinal niche.
bioRxiv · May 6, 2023 · PreprintImmunology