Author

A. Kalverda

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

C.-C. Lin· 1 shared J. E. Ladbury· 1 shared K. M. Suen· 1 shared L. Wieteska· 1 shared Z. Ahmed· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

C.-C. Lin

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1 paper

Recent·Most cited

Grb2 binding induces phosphorylation-independent activation of Shp2

C.-C. Lin, L. Wieteska, K. M. Suen, A. Kalverda, Z. Ahmed, J. E. Ladbury

This study shows Grb2 binding activates Shp2 independently of phosphorylation, and identifies a peptide that blocks this interaction, reducing Shp2 activity and MAPK signaling.

bioRxiv · Nov 29, 2019Cancer Biology