J. E. Ladbury

This study uses expansion microscopy to reveal subdomains within C. elegans P granules and their relationship to other germ granules.

This study shows that RTKs form liquid-liquid phase-separated states with downstream effectors to enhance signaling fidelity.

This study identifies S100A6 as a calcium-dependent regulator of VEGFR trafficking and signaling, integrating these processes in endothelial cell responses to VEGF-A.

The paper investigates how juxtamembrane and C-terminal regions regulate kinase activity in RTKs, identifying key interactions and mutations linked to disease.

This study shows Grb2 binding activates Shp2 independently of phosphorylation, and identifies a peptide that blocks this interaction, reducing Shp2 activity and MAPK signaling.