Pediatric nasal epithelial cells are less permissive to SARS-CoV-2 replication compared to adult cells
Y. Zhu, K. Y. Chew, M. Wu, A. C. Karawita, G. McCallum, L. E. Steele, A. Yamamoto, L. L. Labzin, T. Yarlagadda, A. A. Khromykh, X. Wang, J. Sng, C. J. Stocks, Y. Xia, T. R. Kollmann, , K. R. Short
The paper compares SARS-CoV-2 replication in pediatric and adult nasal epithelial cells, finding lower viral titers in children for ancestral and Delta variants, but higher replication for Omicron.
bioRxiv · Mar 8, 2021 · PreprintMicrobiology