The endosomal sorting adaptor HD-PTP is required for ephrin-B:EphB signalling in cell collapse and motor axon guidance
S. Lahaie, D. Morales, H. Bagci, N. Hamoud, C.-E. Castonguay, J. M. Kazan, G. Desrochers, A. Klar, A.-C. Gingras, A. Pause, J.-F. Cote, A. Kania
This study identifies HD-PTP as an ESCRT adaptor required for ephrin-B:EphB signalling, affecting cell collapse and axon guidance by modulating receptor clustering and degradation.
bioRxiv · Aug 7, 2018Cell Biology