Author

A. Knuuttila

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:mouse· 1

Frequent Co-Authors

A. Hemmes· 2 shared E. W. Verschuren· 2 shared J. Räsänen· 2 shared K. Wennerberg· 2 shared N. Linnavirta· 2 shared A.-L. Levonen· 1 shared J. Bao· 1 shared J. Lomo· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

A. Hemmes

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PI3Kβ inhibition restores ALK inhibitor sensitivity in ALK-rearranged lung cancer

K. Wennerberg, E. W. Verschuren, S. Talwelkar, M. I. Mäyränpää, J. Schüler, N. Linnavirta, A. Hemmes, S. Adinolfi, M. Kankainen, W. Sommergruber, A.-L. Levonen, J. Räsänen, A. Knuuttila

The paper identifies PI3Kβ as a mediator of resistance to ALK inhibitors in ALK-rearranged lung cancer and shows that combining ALK and PI3Kβ inhibitors overcomes resistance.

bioRxiv · Mar 18, 2021 · PreprintCancer Biology

Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments

S. S. Talwelkar, M. I. Mäyranpää, L. Soraas, S. Potdar, J. Bao, A. Hemmes, N. Linnavirta, J. Lomo, J. Räsänen, A. Knuuttila, K. Wennerberg, E. W. Verschuren

This study uses fresh uncultured lung tumor cells to assess drug responses and guide personalized treatment, showing clinical benefit in a refractory cancer case.

bioRxiv · Aug 12, 2020Cancer Biology