Author

A. L. Wolfe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Ku· 1 shared A. N. Liberchuk· 1 shared B. Arroyo· 1 shared C. B. Lebrilla· 1 shared D. Lam· 1 shared E. Toska· 1 shared F. McCormick· 1 shared J. Galeas· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. A. Ku

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2 papers

Recent·Most cited

Effects of N361 Glycosylation on Epidermal Growth Factor Receptor Biological Function

D. Lam, B. Arroyo, A. N. Liberchuk, A. L. Wolfe

This study investigates how N361 glycosylation affects EGFR function, finding that the N361A mutation reduces proliferation and ligand sensitivity while increasing co-localization with HER2 and resistance to antibody inhibition.

bioRxiv · Jul 12, 2024Cancer Biology

UDP-glucose pyrophosphorylase 2, a regulator of glycosylation and glycogen, is essential for pancreatic cancer growth

A. L. Wolfe, Q. Zhou, E. Toska, J. Galeas, A. A. Ku, R. P. Koche, S. Bandyopadhyay, M. Scaltriti, C. B. Lebrilla, F. McCormick, S. E. Kim

This study identifies UGP2 as essential for pancreatic cancer growth by regulating glycogen and N-glycosylation, with potential therapeutic implications.

bioRxiv · Oct 13, 2020 · PreprintCancer Biology