Interaction of NPC2 protein with Lysobisphosphatidic Acid is required for normal endolysosomal cholesterol trafficking
L. A. McCauliff, A. Langan, R. Li, O. Ilnytska, D. Bose, P. C. Kahn, J. Storch
The paper shows NPC2 interacts with LBPA to facilitate cholesterol trafficking from late endosomes/lysosomes, independent of NPC1.
bioRxiv · Feb 24, 2019Biochemistry