Author

A. Leis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. J. Deans· 1 shared M. Sharp· 1 shared M. W. Parker· 1 shared R. Bythell-Douglas· 1 shared S. van Twest· 1 shared V. J. Murphy· 1 shared W. M. Crismani· 1 shared W. Tan· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. J. Deans

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1 paper

Recent·Most cited

Monoubiquitination by the Fanconi Anemia core complex locks FANCI:FANCD2 on DNA in filamentous arrays

W. Tan, S. van Twest, A. Leis, R. Bythell-Douglas, V. J. Murphy, M. Sharp, M. W. Parker, W. M. Crismani, A. J. Deans

This study shows that monoubiquitination of FANCD2 stabilizes the FANCI:FANCD2 complex on DNA and forms filamentous arrays, revealing a mechanism for DNA repair pathway activation.

bioRxiv · Dec 3, 2019Biochemistry