Frequent development of broadly neutralizing antibodies in early life in a large cohort of HIV-infected children
G. G. Fouda, A. Lucier, Y. Fong, S. H. Li, M. Dennis, J. Eudailey, A. Nelson, K. Saunders, C. K. Cunningham, E. McFarland, R. McKinney, M. A. Moody, C. LaBranche, D. Montefiori, S. R. Permar
This study finds that HIV-infected children aged 1-3 years develop broadly neutralizing antibodies with breadth comparable to adults, and overall higher than adults, suggesting early life immune advantages for HIV vaccine development.
bioRxiv · May 7, 2021Immunology