Size-dependent segregation controls macrophage phagocytosis of antibody-opsonized targets
M. H. Bakalar, A. M. Joffe, E. Schmid, S. Son, M. Podolski, D. A. Fletcher
This study identifies an antigen height threshold that regulates macrophage phagocytosis of antibody-opsonized targets, showing that antigens taller than 10 nm impair phagocytosis by disrupting Fc receptor signaling.
bioRxiv · Jan 19, 2018Cell Biology