Systematic identification of conditionally folded intrinsically disordered regions by AlphaFold2
T. R. Alderson, I. Pritisanac, Đesika Kolaric, A. M. Moses, J. D. Forman-Kay
This paper shows AlphaFold2 can predict structures of conditionally folded intrinsically disordered regions with high precision, revealing their prevalence in human and prokaryotic proteins and their association with disease mutations.
bioRxiv · Feb 18, 2022Biochemistry