Molecular Investigations into the Unfoldase Action of Severing Enzymes on Microtubules
R. A. Varikoti, A. Macke, V. Speck, J. L. Ross, R. I. Dima
The paper uses molecular simulations to test a model of microtubule severing by unfolding enzymes, finding that enzyme concentration and placement affect cooperative removal of protofilament fragments.
bioRxiv · Dec 11, 2019Biophysics