Author

A. Maletzko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. P. West· 1 shared G. W. J. Auburger· 1 shared I. Wittig· 1 shared J. Key· 1 shared S. Gispert· 1 shared S. Menissy· 1 shared S. Torres-Odio· 1 shared Y. Lei· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

A. P. West

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1 paper

Recent·Most cited

Loss of mitochondrial protease CLPP activates type I interferon responses through the mtDNA-cGAS-STING signaling axis

S. Torres-Odio, Y. Lei, S. Gispert, A. Maletzko, J. Key, S. Menissy, I. Wittig, G. W. J. Auburger, A. P. West

This study shows that CLPP deficiency causes mtDNA stress, which activates the cGAS-STING pathway and leads to type I interferon responses and antiviral gene expression.

bioRxiv · Aug 30, 2020Immunology