Extraction and high-throughput sequencing of oak heartwood DNA: assessing the feasibility of genome-wide DNA methylation profiling
F. Rossi, A. Crnjar, F. Comitani, R. Feliciano, L. Jahn, G. Malim, L. Southgate, E. Kay, R. Oakey, R. Buggs, A. Moir, L. Kistler, A. Rodriguez Mateos, C. Molteni, R. Schulz
This study assesses the feasibility of genome-wide DNA methylation profiling from oak heartwood, finding that older samples are challenging due to DNA degradation and phenolic compounds.
bioRxiv · Aug 4, 2021Plant Biology