TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients.
A. Sacconi, S. Donzelli, C. Pulito, S. Ferrero, A. Morrone, M. Rigoni, F. Pimipinelli, F. Ensoli, G. Sanguineti, R. Pellini, N. Agrawal, E. Izumchenko, G. Ciliberto, A. Gianni, P. Muti, , G. Blandino
This study finds that TMPRSS2 expression is reduced in head and neck cancer tissues compared to normal tissues and is associated with poorer prognosis.
bioRxiv · Jun 16, 2020Cancer Biology