G. Blandino

The paper compares gene expression in primary and metastatic tumors to their origin and target tissues, finding metastases more resemble target tissues and show reduced cancer hallmark activity.

The paper identifies immune gene signatures associated with response to immunotherapy in HNSCC patients, validated through TCGA and clinical cohorts.

This study identifies distinct roles for YAP and TAZ in NSCLC, showing YAP regulates cell cycle and TAZ regulates extracellular matrix, with differential impacts on growth and migration.

This study finds that TMPRSS2 expression is reduced in head and neck cancer tissues compared to normal tissues and is associated with poorer prognosis.