Sensitive tumor detection, accurate quantification, and cancer subtype classification using low-pass whole methylome sequencing of plasma DNA
M. Paoli, F. Galardi, A. Nardone, C. Biagioni, D. Romagnoli, S. Di Donato, G. M. Franceschini, L. Livraghi, M. Pestrin, G. Sanna, E. Risi, I. Migliaccio, E. Moretti, L. Malorni, L. Biganzoli, , M. Benelli
This paper introduces METER, a computational tool that enables sensitive tumor detection, accurate quantification, and cancer subtype classification using low-pass whole methylome sequencing of plasma DNA.
bioRxiv · Jun 10, 2024 · PreprintCancer Biology