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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
16 papers
Recent·Most cited
R. Babaei-Jadidi, D. Clements, Y. Wu, K. Chen, S. Miller, M. Plate, K. Lim, R. Chambers, E. L. Rawlins, Y. Xu, S. R. Johnson
This study shows mTOR dysregulation in LAM causes IL6 production and senescence in AT2 cells, impairing lung repair, and suggests targeting IL6 may help.
bioRxiv · May 3, 2024 · PreprintCell Biology
K. Lim, E. N. Rutherford, D. Sun, D. J. Van den Boomen, J. R. Edgar, J. Bang, L. E. Matesic, J.-H. Lee, P. J. Lehner, S. J. Marciniak, E. L. Rawlins, J. A. Dickens
bioRxiv · Aug 30, 2023Cell Biology
Z. Dunajova, B. Mateu, P. Radler, K. Lim, P. Velicky, J. G. Danzl, R. W. Wong, J. Elgeti, E. Hannezo, M. Loose
The paper investigates how filament flexibility, density, and chirality influence the formation of chiral and nematic phases in FtsZ filaments during bacterial cell division.
bioRxiv · Dec 15, 2022Biophysics
J. L. Barnes, P. He, M. Yoshida, K. B. Worlock, R. G. H. Lindeboom, C. Suo, J. P. Pett, A. Wilbrey-Clark, E. Dann, L. Mamanova, L. Richardson, A. J. Oliver, A. L. Pennycuick, J. Allen-Hyttinen, I. T. Herczeg, , M. Z. Nikolic
The paper profiles lung immune cells during development using scRNAseq and identifies IL-1β's role in driving epithelial progenitor differentiation.
bioRxiv · Dec 13, 2022Immunology
J. P. Mann, L. Tabara, A. Alvarez-Guaita, L. Dong, A. Haider, K. Lim, P. Tandon, J. E. Minchin, S. O'Rahilly, S. Patel, D. J. Fazakerley, J. Prudent, R. K. Semple, D. B. Savage
The paper shows that loss of Mfn1 promotes adipogenesis in cultured cells, while loss of Mfn2 does not, indicating distinct roles for Mfn1 and Mfn2 in adipocyte differentiation.
bioRxiv · Nov 4, 2022 · PreprintCell Biology
A. Nardone, X. Qui, A. Feiglin, X. Fu, S. Spisak, A. Feit, G. Cohen Feit, Y. Xie, A. Font-Tello, C. Guarducci, F. Hermida Prado, S. Syamala, K. Lim, M. Pun, M. Cornwell, , R. Jeselsohn
This study identifies a unique chromatin state in invasive lobular breast cancer (ILC) driven by FOXA1-ER axis, leading to tamoxifen resistance and poor outcomes.
bioRxiv · Mar 29, 2022Cancer Biology
R. Scheiner, K. Lim, M. D. Meixner, M. S. Gabel
This study compares appetitive learning performance of six European honeybee subspecies in a common apiary, finding that A. m. iberiensis performed significantly worse despite similar sucrose responsiveness.
bioRxiv · Jul 14, 2021Animal Behavior & Cognition
I. Ganeva, K. Lim, J. Boulanger, P. C. Hoffmann, D. B. Savage, W. Kukulski
The paper visualizes lipid droplet interfaces using cryo-ET and shows lipid transfer occurs through closely apposed monolayers with exponential kinetics, suggesting a pressure-driven mechanism.
bioRxiv · Mar 23, 2021Cell Biology
E. J. Schaefer, W. C. Wang, C. A. Meyer, P. Cejas, M. D. Gearhart, E. R. Adelman, I. Fares, A. Apffel, K. Lim, Y. Xie, C. J. Gibson, M. Schenone, H. M. Murdock, E. S. Wang, L. P. Gondek, , R. C. Lindsley
This study shows BCOR and BCORL1 mutations disrupt PRC1.1 function in leukemia by separating its enzymatic core from chromatin targets, leading to treatment resistance.
bioRxiv · Mar 8, 2021 · PreprintCancer Biology
Y. Li, X. Qiu, X. Wang, H. Liu, R. Geck, A. K. Tewari, T. Xiao, A. Font-Tello, K. Lim, J. L. Kristen, M. Morrow, R. Vadhi, P.-L. Kao, A. Jaber, S. Yerrum, , M. Brown
The paper shows that FGFR inhibitors cause SWI/SNF complex dismissal from YAP-dependent enhancers, leading to adaptive resistance in TNBC through epigenetic and metabolic changes.
bioRxiv · Mar 2, 2021Cancer Biology
K. Lim, H. Leverenz, S. Barnum, C. Wademan
This study uses multiple regression analysis to identify factors influencing ureolytic activity in biomineral samples from restrooms, finding significant predictors and highlighting the need to assess gene expression over abundance.
bioRxiv · Feb 18, 2021 · PreprintEcology
X. Wang, C. Tokheim, B. Wang, S. S. Gu, Q. Tang, Y. Li, N. Traugh, Y. Zhang, Z. W. Li, B. Zhang, J. Fu, T. Xiao, W. Li, C. A. Meyer, J. Chu, , X. S. Liu
The paper identifies Cop1 as a modulator of macrophage infiltration and cancer immunotherapy in TNBC by using in vivo CRISPR screens and multi-omics analyses.
bioRxiv · Dec 9, 2020Cancer Biology
S. C. Baca, D. Y. Takeda, J.-H. Seo, J. Hwang, S. Y. Ku, R. Arafeh, T. Arnoff, S. Agarwal, C. Bell, E. O'Connor, X. Qiu, S. Abu Alaiwi, R. I. Corona, M. A. S. Fonseca, C. Giambartolomei, , M. L. Freedman
The paper identifies FOXA1 reprogramming in NEPC and shows its role in maintaining NE lineage features through epigenomic profiling.
bioRxiv · Oct 23, 2020Cancer Biology
P. Cejas, Y. Xie, A. Font-Tello, K. Lim, S. Symala, X. Qiu, A. Tewari, N. Shah, H. Nguyen, R. Patel, L. Brown, I. Coleman, W. M. Hackeng, L. Brosens, K. Dreijerink, , H. W. Long
This study identifies two distinct subtypes of neuroendocrine prostate cancer based on neuronal transcription factors and highlights their epigenetic convergence and therapeutic implications.
bioRxiv · Sep 13, 2020Cancer Biology
S. Silvaraju, N. Menon, H. Fan, K. Lim, S. Kittelmann
This paper develops a high-resolution pheS gene sequencing method to characterize lactobacilli communities at the species level, showing it can detect low-abundance species with high accuracy.
bioRxiv · Sep 9, 2020Microbiology
B. J. Greber, J. M. Perez-Bertoldi, K. Lim, A. T. Iavarone, D. B. Toso, E. Nogales
This paper determines the cryo-EM structure of human CAK, revealing its architecture and inhibitor binding, which informs therapeutic design.
bioRxiv · May 13, 2020Biochemistry